In a patient with suspected ischemic colitis, what laboratory finding strengthens the diagnosis?

In the context of suspected ischemic colitis, an increased level of lactic acid is a significant laboratory finding that strengthens the diagnosis. Ischemic colitis occurs when blood flow to a part of the colon is reduced, leading to tissue hypoxia and subsequent metabolic changes. One of the key metabolic byproducts of anaerobic metabolism, which occurs when tissues are deprived of oxygen, is lactic acid.

As the cells switch to anaerobic metabolism due to compromised blood supply, lactic acid accumulates in the bloodstream, resulting in elevated lactic acid levels. This can be indicative of tissue hypoperfusion and is a common laboratory marker in conditions where ischemia is suspected.

While an increased white blood count could suggest inflammation or infection, and a low platelet count might be seen in various conditions, they are not specific indicators of ischemic colitis. A high hematocrit may occur due to hemoconcentration from dehydration rather than directly indicating ischemic damage. Therefore, an increase in lactic acid is the most relevant finding that supports the diagnosis of ischemic colitis in this clinical scenario.