What age group is most commonly affected by primary biliary cirrhosis?

Primary biliary cirrhosis, now commonly referred to as primary biliary cholangitis, most frequently affects women in the age group of late 40s to early 60s. This autoimmune disease involves chronic inflammation and eventual scarring of the bile ducts in the liver, leading to liver damage.

The age range mentioned reflects the typical demographic that presents with this condition, aligning with the patterns observed in clinical studies. The onset of symptoms often occurs during this time frame, making it the most commonly affected group.

Other age groups, such as children or those significantly older than 70, are not typically associated with the prevalence of primary biliary cholangitis. The disease is relatively rare in younger populations, and its incidence declines in the very elderly, where other comorbidities may complicate the clinical picture. Hence, focusing on the late 40s to early 60s age range provides a clearer understanding of the population most impacted by this condition.