What autoimmune disease symptoms can be associated with primary biliary cirrhosis?

Primary biliary cirrhosis, now more accurately termed primary biliary cholangitis, is an autoimmune liver disease characterized by the gradual destruction of bile ducts within the liver. Individuals with this condition can experience a range of autoimmune-related symptoms due to the systemic nature of autoimmune diseases.

Joint pain is a common symptom associated with various autoimmune conditions, including primary biliary cholangitis. The inflammatory processes that underpin autoimmune disorders can lead to arthralgia, which is the medical term for pain in the joints.

Skin rashes can also arise in patients with primary biliary cholangitis. This condition may present with various dermatological manifestations, including specific rashes like xanthomas or pruritus due to bile salt accumulation, which can lead to scratching and skin changes.

Fatigue is another hallmark symptom often reported by patients with primary biliary cholangitis. The chronic nature of the disease, along with the liver's impaired function, can contribute significantly to feelings of tiredness and low energy, which are typical complaints in autoimmune diseases.

Since all these symptoms—joint pain, skin rashes, and fatigue—can occur in patients suffering from primary biliary cholangitis, the correct choice encompasses the full spectrum of potential manifestations of this autoimmune disorder