What is an appropriate intervention for a patient with new-onset nighttime cough and clear chest findings on examination?

In the case of a patient presenting with a new-onset nighttime cough accompanied by clear chest findings, initiating an oral antihistamine is a suitable intervention. The nighttime cough may suggest an allergic trigger or environmental irritants that are more pronounced during the night. Antihistamines can help reduce the symptoms associated with allergies, including cough, by blocking the effects of histamine, which is released during allergic reactions and can lead to respiratory symptoms such as coughing.

Humidifiers can provide comfort and alleviate dry air but may not directly address underlying allergic responses that might be responsible for the cough. While nasal saline irrigation can help keep nasal passages moist and clear of allergens, it primarily addresses nasal symptoms rather than cough. Referring for an allergy test may be warranted if symptoms persist or if there is a need for further evaluation; however, it is not an immediate intervention for managing current symptoms. Therefore, choosing to initiate an oral antihistamine directly targets the likely cause of the patient's nighttime cough.