What is the classic triad of symptoms associated with Henoch-Schonlein purpura?

Henoch-Schonlein purpura (HSP), also known as IgA vasculitis, is characterized by a classic triad of symptoms that includes abdominal pain, a vasculitic rash (often purpuric), and renal involvement.

The abdominal pain typically arises from intestinal vasculitis or mesenteric ischemia, leading to symptoms like cramping or even gastrointestinal bleeding. The vasculitic rash, which is usually palpable purpura, primarily occurs on the buttocks and legs and is a key diagnostic feature of the condition. Renal involvement can manifest as hematuria and proteinuria, indicating the presence of IgA deposition and inflammation in the kidneys.

In summary, the combination of these three manifestations—abdominal pain, a characteristic rash, and kidney issues—provides a clear clinical picture that is crucial for diagnosing HSP. Understanding these symptoms allows for timely management and intervention.