What is the first-line treatment for enterobiasis?

The first-line treatment for enterobiasis, commonly known as pinworm infection, is mebendazole. This anthelmintic medication works by inhibiting the microtubule formation in the pinworms, which effectively disrupts their metabolism and leads to their death. Mebendazole is favored for its efficacy and safety profile, making it a go-to option for treating this common parasitic infection, particularly in children.

While albendazole is another effective treatment for enterobiasis, it is typically used in cases where mebendazole is not available or in specific patient populations. Pyrantel pamoate can also treat pinworms, but mebendazole remains the most extensively studied and widely recommended first-line therapy. Antihistamines do not have any effect on treating enterobiasis, as they do not target the parasites directly. Thus, mebendazole remains the cornerstone of treatment for pinworm infections.