What is the most appropriate medication to add for a 50-year-old female with type II diabetes and mild protein in the urine?

In the case of a 50-year-old female with type II diabetes who has mild protein in her urine, the most appropriate medication to consider is lisinopril. Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor, which is particularly beneficial in patients with diabetes. Its primary role in this context is to provide renal protection, especially in the presence of proteinuria. This medication can help reduce the progression of nephropathy in diabetic patients by lowering intraglomerular pressure and providing protective effects on the kidneys.

The presence of mild protein in the urine indicates a risk for diabetic nephropathy, making lisinopril an important addition to her treatment regime. Using this medication can also help manage blood pressure, which is a significant consideration in individuals with diabetes.

While metformin is a cornerstone treatment for managing type II diabetes, it does not specifically address the nephroprotective needs in this case. Similarly, simvastatin would be appropriate for managing dyslipidemia, but it does not target the renal concerns associated with proteinuria. Glyburide, a sulfonylurea, is used to increase insulin secretion from the pancreas but is not focused on the renal protection needed for someone presenting with protein in