What medication is NOT typically used in the treatment of Kawasaki disease?

Kawasaki disease is an acute vasculitis that primarily affects children and is characterized by a prolonged fever and inflammation in systemic blood vessels. The cornerstone of treatment for Kawasaki disease includes aspirin and intravenous immunoglobulin (IVIG). Aspirin helps reduce inflammation and fever, and IVIG is essential in preventing coronary artery complications that can arise from the disease.

Corticosteroids are sometimes used in more severe cases or as adjunctive therapy, particularly when the patient does not respond adequately to IVIG. However, they are not the primary treatment modality and are used selectively.

Antihistamines are typically used for allergic reactions and are not indicated in the treatment of Kawasaki disease, as they do not address the underlying inflammatory process critical in this condition. Therefore, they are not part of the standard treatment protocol for Kawasaki disease, making this choice the correct answer to the question.