What type of conditions are associated with recurrent pregnancy losses?

Recurrent pregnancy loss, defined as the occurrence of two or more consecutive pregnancy losses, can be attributed to a variety of factors that include immunologic, anatomical, and genetic components.

Immunologic factors may involve issues with the immune response, such as antiphospholipid syndrome, where the body mistakenly targets its own tissues, leading to complications during pregnancy. Anatomical factors refer to structural abnormalities of the uterus, such as septate uterus or fibroids, which can impede proper implantation or support of the developing fetus. Genetic factors can involve chromosomal abnormalities in either parent that can lead to embryonic dysfunction and loss.

This multifactorial nature of recurrent pregnancy loss underscores why a comprehensive evaluation is important for affected individuals. Addressing only one set of factors, such as genetic or environmental alone, would not encompass the full range of potential causes, indicating the necessity for a holistic approach in diagnosis and management. Thus, the inclusion of immunologic, anatomical, and genetic factors provides a more complete understanding of why recurrent pregnancy losses may occur.