Which class of medications modestly raises HDL cholesterol levels?

Statins are principally known for their ability to lower low-density lipoprotein (LDL) cholesterol levels, which is a primary target in the management of dyslipidemia and prevention of cardiovascular disease. In addition to this LDL-lowering effect, statins have been shown to modestly raise high-density lipoprotein (HDL) cholesterol levels. HDL cholesterol is often referred to as "good" cholesterol because it helps remove other forms of cholesterol from the bloodstream, thereby providing a protective effect against heart disease. This dual benefit of lowering LDL while simultaneously increasing HDL makes statins a cornerstone treatment in managing cholesterol levels and reducing cardiovascular risk.

The other classes of medications listed do not have a significant impact on HDL cholesterol levels. Diuretics primarily work by promoting fluid balance and have minimal effects on lipid profiles. Beta blockers are mainly used for managing hypertension and heart problems, and while they can indirectly affect lipid levels, they are not known for raising HDL cholesterol significantly. Anticoagulants are utilized to prevent blood clotting and have no direct effects on cholesterol metabolism. Hence, in the context of raising HDL cholesterol, statins are the most relevant class of medications.