Which renal findings can be seen in Henoch-Schonlein purpura?

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In Henoch-Schonlein purpura (HSP), which is a small-vessel vasculitis often seen in children, renal involvement is common. The typical findings in the kidneys include hematuria (the presence of blood in the urine) and proteinuria (the presence of excess protein in the urine). These abnormalities are due to the deposition of immune complexes in the glomeruli, leading to inflammation and kidney damage.

Hematuria can present as macroscopic or microscopic blood in the urine, while proteinuria indicates that the glomerular filtration barrier has been compromised. These findings are significant as they suggest that the kidneys are affected by the systemic vasculitis that characterizes HSP.

Oliguria and edema can occur in renal disease, but in the context of HSP, hematuria and proteinuria are more classic findings. Rising creatinine may happen if renal impairment progresses, but it is not as immediate or characteristic as the other two. Isosthenuria refers to urine that has the same osmolality as plasma, which is not specifically linked to HSP. Therefore, the presence of hematuria and proteinuria is the hallmark renal manifestation seen in this condition.

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