Which symptom would be least common in TORCH infections?

In the context of TORCH infections—which include infections caused by Toxoplasmosis, Other (such as syphilis), Rubella, Cytomegalovirus (CMV), and Herpes Simplex Virus (HSV)—the least common symptom is severe hypotonia.

Hypotonia, or decreased muscle tone, can be observed in various pediatric conditions; however, it is not a hallmark feature of most TORCH infections. While some of these infections can lead to neurologic issues or developmental concerns, hypotonia is not specifically associated or commonly recognized as a direct symptom in these infections.

On the other hand, lesions such as hepatosplenomegaly, generalized rash, and bleeding diathesis are more characteristic of certain TORCH infections. For example, hepatosplenomegaly is frequently noted in congenital infections like CMV and syphilis. Generalized rashes can occur in rubella. Bleeding diathesis may be observed in congenital infections with certain viruses, such as cytomegalovirus or congenital syphilis.

Thus, severe hypotonia is the least common symptom associated with TORCH infections compared to the other symptoms listed.